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Cystic fibrosis medical care is too big to fit into a clinicians pocket and too small to justify a place on a reference book shelf it is described as a practical and easy to use reference book and by the authors as an introduction to the principles and practices of cystic fibrosis medical carecystic fibrosis facts medical author melissa conrad stppler md cystic fibrosis cf is an inherited disease that affects the secretory glands including the mucus and sweat glands cystic fibrosis mostly affects the lungs pancreas liver intestines sinuses and sex organs cf is due to a mutation in the cf gene on chromosome 7cystic fibrosis cf is an inherited disease of the mucus and sweat glands it affects mostly your lungs pancreas liver intestines sinuses and sex organs cf causes your mucus to be thick and sticky the mucus clogs the lungs causing breathing problems and making it easy for bacteria to grow this can lead to repeated lung infections and as a result of the complex and multisystemic involvement of cystic fibrosis cf and the need for care by specialists treatment and follow up care at specialty centers with multidisciplinary care teams ie cystic fibrosis centers is recommended at the time of initial confirmation of the etiology more than 1000 possible changes can occur in cftr to cause cystic fibrosis but approximately 70 of all patients with cystic fibrosis have the same defect f508 1 this defect is a deletion of 3 bases that causes the loss of the protein phenylalanine 2 patients who have a complete loss of the cftr gene have a clinical phenotype representative of pancreatic disease severe pulmonary

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