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BOOK SUMMARY :

Leading scientists offer detailed profiles of ten protein drugs currently in development the case histories of these important new compounds are described from the perspective of their formulation characterization and stabilityformulation characterization and stability of protein drugs case histories edited by rodney pearlman megabios corporation burlingame california andconclusions g csf is an extremely well known and well characterized molecule both the natural glycosylated form and the e coli produced nonglycosylated form are biologically activea thorough understanding of the primary secondary and tertiary structures has enabled a rational approach to purification folding and formulationabscom formulation characterization and stability of protein drugs case histories pharmaceutical biotechnology 9780306453328 and a great the case histories of these important new compounds are described from the perspective of their formulation characterization and stability this readya comparison of tryptic peptide maps obtained for iex 1 and iex 3 is given in fig 3 with peptide assignments for the collected peak fractions given in table 1iex 1 gave two forms of the lc25 42 peptide with asp peak d30 or asn peak n30 at the asn30 position consistent with an underlying structure with one deamidated asp30 light chain and one light chain with the expected asn30

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